1-(4-氯苯基)-2-甲基-2-丙醇合成路线 （共 20 条）
反应条件
2: 79 percent / diethyl ether View Scheme
参考文献
Chemische Berichte, , vol. 114, # 12 p. 3813 - 3830
反应条件
Ambient temperatureIrradiationrelative yields of products for different substituents;
参考文献
Tetrahedron, , vol. 41, # 8 p. 1435 - 1440
反应条件
2,3-dimethyl aniline in water
参考文献
Astra Lakemedel Aktiebolag
Patent: US4237311 A1, 1980 ;
US 4237311 A
反应条件
1: H2SO4, AcOH 2: aq. HCl / aq. ethanol / Heating View Scheme
参考文献
Pathway Therapeutics Inc.
Patent: US2012/252802 A1, 2012 ;
US 20120252802 A1
反应条件
1: H2SO4, AcOH 2: aq. HCl / aq. ethanol / Heating 3: Py View Scheme
参考文献
Ferrari,G.
Farmaco, Edizione Scientifica, 1960 , vol. 15, p. 337 - 342
反应条件
hydrogenchloride; sulfuric acid; sodium cyanide; acetic acid 1.) 70 deg C, 2 h, 2.) ether; Yield givenMultistep reaction;
参考文献
Adams, Mortimer H.; Ameer, Farouk; Green, Ivan R.; Syce, James A.
Synthetic Communications, 1999 , vol. 29, # 14 p. 2419 - 2430
反应条件
potassium hydrogensulfate; hydroquinone
参考文献
Yandovskii,V.N.; Temnikova,T.I.
Journal of Organic Chemistry USSR (English Translation), 1968 , vol. 4, p. 973 - 974
Zhurnal Organicheskoi Khimii, 1968 , vol. 4, # 6 p. 1004 - 1006
反应条件
sulfuric acid; acetic acid
参考文献
Ferrari,G.
Farmaco, Edizione Scientifica, 1960 , vol. 15, p. 337 - 342
反应条件
[bis(acetoxy)iodo]benzene; palladium diacetate; lithium carbonate in hexafluorobenzene
T=100°C; 36 h;
参考文献
Wang, Xisheng; Lu, Yi; Dai, Hui-Xiong; Yu, Jin-Quan
Journal of the American Chemical Society, 2010 , vol. 132, # 35 p. 12203 - 12205
反应条件
1: PhNMe2 / diethyl ether
2: NH3 / ethanol
View Scheme
参考文献
Lindberg; Thorberg; Bengtsson; Renyi; Ross; Ogren
Journal of Medicinal Chemistry, 1978 , vol. 21, # 5 p. 448 - 456
