1,5-二苯基吡咯烷-2-酮合成路线 （共 9 条）
反应条件
triethylsilane; aluminium trifluoromethanesulphonate in acetonitrile
1 h; Reflux;
参考文献
Qi, Jianguo; Sun, Chenbin; Tian, Yulin; Wang, Xiaojian; Li, Gang; Xiao, Qiong; Yin, Dali
Organic Letters, 2014 , vol. 16, # 1 p. 190 - 192
反应条件
polyphosphoric acid
T=105 - 110°C; 1 h;
参考文献
Vas'Kevich; Daniluk, I. Yu.; Vovk
Russian Journal of Organic Chemistry, 2013 , vol. 49, # 8 p. 1175 - 1181
Zh. Org. Khim., 2013 , vol. 49, # 8 p. 1192 - 1198,7
反应条件
aniline hydrochloric acid
T=180°C;
参考文献
Pernot; Willemart
Bulletin de la Societe Chimique de France, 1953 , p. 324
反应条件
potassium hydroxide; palladium on activated charcoal; Lindlar's catalyst; ethanol
Hydrogenation;
参考文献
Meyer; Vaughan
Journal of Organic Chemistry, 1957 , vol. 22, p. 1560,1563
反应条件
1: chloroform; nitrosyl chloride
2: palladium/calcium carbonate; ethanol; KOH-solution / Hydrogenation
View Scheme
参考文献
Meyer; Vaughan
Journal of Organic Chemistry, 1957 , vol. 22, p. 1560,1563
反应条件
1: sodium borate; ethanol
2: unter Entfernen des entstehenden Wassers
View Scheme
参考文献
Meyer; Vaughan
Journal of Organic Chemistry, 1957 , vol. 22, p. 1560,1563
反应条件
potassium tert-butylate; p-toluenesulfonyl chloride
1.) HMPA, THF, 0 deg C, 1 h, 2.) 50 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Takahata, Hiroki; Wang, Eng-Chi; Yamazaki, Takao
Synthetic Communications, 1988 , vol. 18, # 10 p. 1159 - 1166
反应条件
1: 1.) n-BuLi, 2.) BF3-Et2O / 1.) THF, HMPA, -72 deg C, 30 min, 2.) -72 deg C -> 0 deg C, 2 h
2: 1.) t-BuOK, 2.) TsCl / 1.) HMPA, THF, 0 deg C, 1 h, 2.) 50 deg C, 3 h
View Scheme
参考文献
Takahata, Hiroki; Wang, Eng-Chi; Yamazaki, Takao
Synthetic Communications, 1988 , vol. 18, # 10 p. 1159 - 1166
反应条件
1: 1.) n-BuLi, 2.) BF3-Et2O / 1.) THF, HMPA, -72 deg C, 30 min, 2.) -72 deg C -> 0 deg C, 2 h
2: 1.) t-BuOK, 2.) TsCl / 1.) HMPA, THF, 0 deg C, 1 h, 2.) 50 deg C, 3 h
View Scheme
参考文献
Takahata, Hiroki; Wang, Eng-Chi; Yamazaki, Takao
Synthetic Communications, 1988 , vol. 18, # 10 p. 1159 - 1166
