1: With sodium dihydrogen phosphate dihydrate in water; acetonitrile T=-15°C; 0.166667 h; 2: With dihydrogen peroxide in water; acetonitrile 0.0833333 h; 3: With sodium chlorite in water; acetonitrile 1 h;

toluene-4-sulfonic acid in diethyl ether 16 h; Ambient temperature;

1.1: pyridinium p-toluenesulfonate / chloroform / 18 h / 20 °C / |Inert atmosphere 2.1: oxalyl dichloride; dimethyl sulfoxide / chloroform / 2 h / -55 °C 2.2: 0.75 h / -55 - 0 °C 3.1: sodium dihydrogen phosphate dihydrate / water; acetonitrile / 0.17 h / -15 °C 3.2: 0.08 h 3.3: 1 h View Scheme

1.1: oxalyl dichloride; dimethyl sulfoxide / chloroform / 2 h / -55 °C 1.2: 0.75 h / -55 - 0 °C 2.1: sodium dihydrogen phosphate dihydrate / water; acetonitrile / 0.17 h / -15 °C 2.2: 0.08 h 2.3: 1 h View Scheme

1.1: pyridinium p-toluenesulfonate / chloroform / 18 h / 20 °C / |Inert atmosphere 2.1: oxalyl dichloride; dimethyl sulfoxide / chloroform / 2 h / -55 °C 2.2: 0.75 h / -55 - 0 °C 3.1: sodium dihydrogen phosphate dihydrate / water; acetonitrile / 0.17 h / -15 °C 3.2: 0.08 h 3.3: 1 h View Scheme

sulfuric acid T=60°C; 15 h;