(E)-3-(1-吡咯烷酮)巴豆酸乙酯合成路线 （共 11 条）
参考文献
Vohra, Ramandeep Kaur; Renaud, Jean-Luc; Bruneau, Christian
Synthesis, 2007 , # 5 p. 731 - 738
反应条件
in tert-butyl alcohol Addition; 4 h; Heating;
参考文献
Felice, Elena; Fioravanti, Stefania; Pellacani, Lucio; Tardella, Paolo A.
Tetrahedron Letters, 1999 , vol. 40, # 23 p. 4413 - 4416
反应条件
1: Et3N / CH2Cl2 / 24 h
2: 56 percent / CH2Cl2
3: 84 percent / HCl; water / CH2Cl2 / 72 h / 20 °C
View Scheme
参考文献
Kostyuk, Alexandr N.; Svyaschenko, Yurii V.; Volochnyuk, Dmitriy M.; Lysenko, Nikolai V.; Tolmachev, Andrei A.; Pinchuk, Alexandr M.
Tetrahedron Letters, 2003 , vol. 44, # 34 p. 6487 - 6491
反应条件
triethylamine in ethanol
T=20°C;
参考文献
Zamponi, Gerald W.; Stotz, Stephanie C.; Staples, Richard J.; Andro, Tina M.; Nelson, Jared K.; Hulubei, Victoria; Blumenfeld, Alex; Natale, Nicholas R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 87 - 96
反应条件
triethylamine in ethanol
T=20°C;
参考文献
FIBROGEN, INC.
Patent: WO2009/73669 A1, 2009 ;
Location in patent: Page/Page column 69 ;
WO 2009/073669 A1
反应条件
1: pyridine-4-carboxaldoxime With pyridine; N-chloro-succinimide in chloroform
T=20°C; 0.75 h;
2: (E)-3-pyrrolidinobut-2-enoic acid ethyl ester With triethylamine in chloroform
T=20 - 50°C; 31.5 h;
参考文献
Buettelmann, Bernd; Jakob-Roetne, Roland; Knust, Henner; Lucas, Matthew C.; Thomas, Andrew
Patent: US2009/143371 A1, 2009 ;
Location in patent: Page/Page column 40 ;
US 20090143371 A1
反应条件
pyridine; N-chloro-succinimide; triethylamine in n-heptane; chloroform
参考文献
Buettelmann, Bernd; Jakob-Roetne, Roland; Knust, Henner; Thomas, Andrew
Patent: US2009/143385 A1, 2009 ;
反应条件
triethylamine in ethanol
T=0 - 20°C;
参考文献
Gerritz, Samuel; Shi, Shuhao; Zhu, Shirong
Patent: US2006/287287 A1, 2006 ;
Location in patent: Page/Page column 22 ;
US 20060287287 A1
反应条件
triethylamine in ethanol
T=20°C;
参考文献
Zamponi, Gerald W.; Stotz, Stephanie C.; Staples, Richard J.; Andro, Tina M.; Nelson, Jared K.; Hulubei, Victoria; Blumenfeld, Alex; Natale, Nicholas R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 87 - 96
反应条件
triethylamine in ethanol
T=20°C;
参考文献
Zamponi, Gerald W.; Stotz, Stephanie C.; Staples, Richard J.; Andro, Tina M.; Nelson, Jared K.; Hulubei, Victoria; Blumenfeld, Alex; Natale, Nicholas R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 87 - 96
