DL-2,4-二氯苯丙氨酸合成路线 （共 8 条）
反应条件
sulfuric acid; acetic acid T=80°C; 8 h; Microwave irradiation;
参考文献
WO2012/58065 A1, ;
Page/Page column 95 ;
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3502
反应条件
1: ethanol 2: concentrated aqueous HBr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3502
反应条件
tris-(2-chloro-ethyl)-amine; sulfuric acid; benzene
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 7, p. 912,914, 916
反应条件
1: aqueous KOH 2: HN3; H2SO4; benzene View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 7, p. 912,914, 916
反应条件
1: sodium ethylate; ethanol 2: aqueous KOH 3: HN3; H2SO4; benzene View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 7, p. 912,914, 916
反应条件
sodium hydroxide; oxygen; tri-(hydroxymethyl)-methylamine in water T=30°C; pH=7.3; 3 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Zhang, Zizhang
Tetrahedron Letters, 2008 , vol. 49, # 45 p. 6468 - 6470
反应条件
sodium hydroxide; oxygen T=30°C; pH=7.3; 22 h; aq. bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 4 p. 1129 - 1131
