1-(三甲基硅氧基)-3,4-二氢苯合成路线 （共 16 条）
反应条件
1: cyclohexenon With lithium hexamethyldisilazane in tetrahydrofuran T=4°C; 0.5 h; 2: chloro-trimethyl-silane in tetrahydrofuran T=4°C; 0.75 h;
参考文献
Romanski, Steffen; Ruecker, Hannelore; Stamellou, Eleni; Guttentag, Miguel; Neudoerfl, Joerg-Martin; Alberto, Roger; Amslinger, Sabine; Yard, Benito; Schmalz, Hans-Guenther
Organometallics, 2012 , vol. 31, # 16 p. 5800 - 5809
反应条件
n-butyllithium; N2 in tetrahydrofuran; hexane
参考文献
G.D. Searle and Co.
Patent: US6046190 A1, 2000 ;
US 6046190 A
Title/Abstract Full Text Show Details
G. D. Searle and Co.
Patent: US5968942 A1, 1999 ;
US 5968942 A
反应条件
triethylamine; lithium bromide in tetrahydrofuran 1) -15 deg C, 1 h; 2) 40 deg C, 24 h; Yield given. Yields of byproduct given;
参考文献
Acta Chemica Scandinavica, , vol. 43, # 2 p. 188 - 192
反应条件
triethylamine in diethyl ether T=20°C; 2 h;
参考文献
Tetrahedron Letters, , vol. 22, # 23 p. 2151 - 2154
参考文献
Noda, Daisuke; Sunada, Yusuke; Hatakeyama, Takuji; Nakamura, Masaharu; Nagashima, Hideo
Chemical Communications, 2012 , vol. 48, # 100 p. 12231 - 12233
反应条件
1: T=140°C; Diels-Alder reaction; 2 h; 2: With potassium carbonate in methanol 0.166667 h; Further stages.;
参考文献
Ashburn, Bradley O.; Carter, Rich G.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 2 p. 255 - 257
反应条件
1: T=140°C; 3 h; Neat (no solvent); 2: With methanol; potassium carbonate T=20°C; 0.25 h;
参考文献
Abid, Obaid-Ur-Rahman; Nawaz, Muhammad; Ibad, Muhammad Farooq; Khera, Rasheed Ahmad; Iaroshenko, Viktor; Langer, Peter
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2185 - 2191
反应条件
T=250°C; Diels-Alder reaction; P=3750.38 Torr; Neat (no solvent);
参考文献
Organic Process Research and Development, , vol. 16, # 5 p. 1114 - 1120
反应条件
1) 150 deg C, 15 h, 2) 1N NaOMe, MeOH, r.t., 3 h; Yield given. Multistep reaction;
参考文献
Werstiuk, N. H.; Yeroushalmi, S.; Guan-Lin, Hong
Canadian Journal of Chemistry, 1992 , vol. 70, # 3 p. 974 - 980
反应条件
oxygen O2, singlet; thiamine diphosphate in dichloromethane T=-78°C; 10 h; Irradiation;
参考文献
Tetrahedron Letters, , vol. 24, # 40 p. 4291 - 4294
