2-氯-5-甲氧基苯甲酸甲酯合成路线 (共 7 条)
反应条件
1: With lithium hydroxide; water in tetrahydrofuran T=20°C; 21 h; Heating / reflux; 2: With hydrogenchloride in water pH=1;
参考文献
WO2008/64432 A1, ;
Page/Page column 59-60 ;
WO 2008/064432 A1
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Wilkinson,R.G. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 637 - 643
反应条件
1: LiAlH4 2: SOCl2 View Scheme
参考文献
Wilkinson,R.G. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 637 - 643
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=40°C; 21 h;
参考文献
Gunosewoyo, Hendra; Guo, Jun Liu; Bennett, Maxwell R.; Coster, Mark J.; Kassiou, Michael
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 13 p. 3720 - 3723
反应条件
(i) SOCl2, (ii) /BRN= 1098229/; Multistep reaction;
参考文献
Wilkinson,R.G. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 637 - 643
反应条件
(i) Cl2, (ii) HCl; Multistep reaction;
参考文献
Bhati,A.
Tetrahedron, 1962 , vol. 18, p. 1519 - 1526
反应条件
1: LiAlH4
2: PBr3
View Scheme
参考文献
Bhati,A.
Tetrahedron, 1962 , vol. 18, p. 1519 - 1526