(Z)-6-二十一碳烯-11-酮合成路线 （共 124 条）
反应条件
1.1: C32H41N3O4Ru / tetrahydrofuran / 5 h / 20 °C / |Inert atmosphere; |Glovebox 2.1: oxalyl dichloride / dimethyl sulfoxide; dichloromethane / 0.33 h / -78 °C / |Inert atmosphere 2.2: -78 - 20 °C / |Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 1 p. 310 - 314
Angew. Chem., , vol. 125, # 1 p. 328 - 332,5
反应条件
1.1: tert.-butyl lithium / diethyl ether / 1 h / -78 - 20 °C / |Inert atmosphere 1.2: -78 - 20 °C / |Inert atmosphere 2.1: C32H41N3O4Ru / tetrahydrofuran / 5 h / 20 °C / |Inert atmosphere; |Glovebox 3.1: oxalyl dichloride / dimethyl sulfoxide; dichloromethane / 0.33 h / -78 °C / |Inert atmosphere 3.2: -78 - 20 °C / |Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 1 p. 310 - 314
Angew. Chem., , vol. 125, # 1 p. 328 - 332,5
反应条件
pyridinium chlorochromate in dichloromethane
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 69, # 5 p. 957 - 965
反应条件
1: 1) MgCl2, K, KI / 1) THF, reflux, 2.5 h, 2) a) -78 deg C, 1 h, b) to r.t., 0.5 h 2: p-toluenesulfonic acid / 3 h / Heating 3: glacial acetic acid, water / 4 h 4: 1) potassium tert-butoxide / 1) THF, r.t., 1 h, 2) THF, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 16 p. 4560 - 4562
反应条件
1: p-toluenesulfonic acid / 3 h / Heating 2: glacial acetic acid, water / 4 h 3: 1) potassium tert-butoxide / 1) THF, r.t., 1 h, 2) THF, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 16 p. 4560 - 4562
参考文献
Naoshima, Yoshinobu; Ike, Hisashi; Ogawa, Tomiaki; Nakayama, Toru; Kondo, Hirokiyo
Agricultural and Biological Chemistry, 1984 , vol. 48, # 8 p. 2151 - 2154
反应条件
hydrogenchloride 1.) ether, room temp.; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 25, # 2 p. 223 - 226
反应条件
1: 88 percent / TMSOTf / 0 °C 2: 2) hydrochloric acid / 1.) ether, room temp. View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 2 p. 223 - 226
反应条件
1: 52 percent 2: 80 percent / Cu(I)Br / Na<H2Al(-O-(CH2)2-O-CH3)2> View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 50 p. 6171 - 6174
反应条件
2: 52 percent 3: 80 percent / Cu(I)Br / Na<H2Al(-O-(CH2)2-O-CH3)2> View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 50 p. 6171 - 6174
