(Z)-6-二十一碳烯-11-酮合成路线 （共 124 条）
反应条件
1: 1.) KOt-C4H9, 2.) C5H5N / 1.) THF, 0 deg C - -78 deg C - RT, 2.) (C2H5)2O, RT 2: 454 - 650 °C / 0.05 - 0.3 Torr / flash vacuum pyrolysis 4: 75 percent / 2-propylmagnesium bromide / (Ph3P)2NiCl2 / tetrahydrofuran; diethyl ether / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 22, # 36 p. 3463 - 3466
反应条件
2: 75 percent / 2-propylmagnesium bromide / (Ph3P)2NiCl2 / tetrahydrofuran; diethyl ether / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 22, # 36 p. 3463 - 3466
反应条件
1: 454 - 650 °C / 0.05 - 0.3 Torr / flash vacuum pyrolysis 3: 75 percent / 2-propylmagnesium bromide / (Ph3P)2NiCl2 / tetrahydrofuran; diethyl ether / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 22, # 36 p. 3463 - 3466
反应条件
in tetrahydrofuran; diethyl ether; hexane 2 h; Ambient temperature;
参考文献
Cahiez; Alexakis; Normant
Tetrahedron Letters, 1980 , vol. 21, # 15 p. 1433 - 1436
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride; copper(I) bromide
参考文献
Bestmann, Hans Jurgen; Schmidt, Martin
Tetrahedron Letters, 1985 , vol. 26, # 50 p. 6171 - 6174
反应条件
1.1: 88 percent / pyridine / 24.5 h / 0 °C 2.1: CuI / tetrahydrofuran / -30 - 20 °C 2.2: tetrahydrofuran / 2 h / 40 °C 2.3: 62 percent / 1 M AcOH / hexane / 2 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 3 p. 935 - 942
反应条件
1: 1.) NaH; 2.) NaI / 1.) toluene; 2.) toluene, DMF, reflux 2: 91 percent / hydrogen, quinoline / 5percent Pd-BaSO4 / methanol / 3 h / 760 Torr View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 57, # 4 p. 2015 - 2016
反应条件
1: 81 percent 2: 88 percent / H2 / Rh/C / 2327.2 Torr 3: Jones reagent 4: 18 percent / Li, NH3 / tetrahydrofuran 5: PCC View Scheme
参考文献
Synthetic Communications, , vol. 13, # 7 p. 621 - 628
反应条件
1: 88 percent / H2 / Rh/C / 2327.2 Torr 2: Jones reagent 3: 18 percent / Li, NH3 / tetrahydrofuran 4: PCC View Scheme
参考文献
Synthetic Communications, , vol. 13, # 7 p. 621 - 628
反应条件
1: 97 percent / hydrogen, quinoline / Pd/CaCO3 2: 1.15 g / triethylamine / CH2Cl2 / 0 °C 3: 1.25 g / sodium iodide / acetone / 3 h / Heating 4: 90 percent / sodium hydride, DMSO / diethyl ether / 2.5 h / Ambient temperature 5: 100 percent / conc. HCl / CH2Cl2; diethyl ether / 0.17 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 13, # 5 p. 379 - 386
