(Z)-6-二十一碳烯-11-酮合成路线 （共 124 条）
反应条件
1: sodium acetate, hydroxylamine hydrochloride / ethanol / Ambient temperature 2: pyridine / Ambient temperature 3: 88 percent / TMSOTf / 0 °C 4: 2) hydrochloric acid / 1.) ether, room temp. View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 2 p. 223 - 226
反应条件
1: 66 percent / Me3SiCl, NaI / acetonitrile / Ambient temperature 2: acetone; H2O / 24 h / Heating 3: 1) Et2O, 2) H3O+ View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 26 p. 3059 - 3062
反应条件
1: 93 percent / NaH / toluene / 2 h / 100 °C 2: 83 percent / K2CO3 / butan-2-one / 20 h / Heating 3: 84 percent / aq. NaOH / methanol / 48 h / 80 °C View Scheme
参考文献
Bioscience, biotechnology, and biochemistry, , vol. 67, # 7 p. 1559 - 1567
反应条件
1: 83 percent / K2CO3 / butan-2-one / 20 h / Heating 2: 84 percent / aq. NaOH / methanol / 48 h / 80 °C View Scheme
参考文献
Bioscience, biotechnology, and biochemistry, , vol. 67, # 7 p. 1559 - 1567
反应条件
1: BuLi / tetrahydrofuran / 2 h / Ambient temperature 2: 1.23 g / aq. HCl / tetrahydrofuran View Scheme
参考文献
Synthetic Communications, , vol. 16, # 13 p. 1723 - 1730
反应条件
1: 1.85 g / LiBr / acetone / 5 h / Ambient temperature 2: BuLi / tetrahydrofuran / 2 h / Ambient temperature 3: 1.23 g / aq. HCl / tetrahydrofuran View Scheme
参考文献
Synthetic Communications, , vol. 16, # 13 p. 1723 - 1730
反应条件
1: 92 percent / DIBAL-H / tetrahydrofuran; hexane / 0.5 h / -78 °C 2: 83 percent / tetrahydrofuran / 1.) -78 deg C, 1 h, 2.) room temperature, 1 h 3: PCC View Scheme
参考文献
Synthetic Communications, , vol. 17, # 7 p. 893 - 900
反应条件
1: 2.) NaBH4, 2 M NaOH / 1.) acetic acid, room temperature, 24 h, 2.) 0 deg C, 1 h 2: 75 percent / LAH / tetrahydrofuran / 3 h / Heating 3: 70 percent / pyridiniumchlorochromate / CH2Cl2 / 1.5 h / Ambient temperature 4: 50 percent / potassiumtertiarybutoxide / tetrahydrofuran View Scheme
参考文献
Synthetic Communications, , vol. 17, # 15 p. 1845 - 1850
反应条件
1: 80 percent / aq. NaOH, tetra-n-butylammonium hydroxide / CH2Cl2 / 12 h / 0 °C 2: 90 percent / sodium hydride, DMSO / diethyl ether / 2.5 h / Ambient temperature 3: 100 percent / conc. HCl / CH2Cl2; diethyl ether / 0.17 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 13, # 5 p. 379 - 386
反应条件
1: 70 percent / pyridiniumchlorochromate / CH2Cl2 / 1.5 h / Ambient temperature 2: 50 percent / potassiumtertiarybutoxide / tetrahydrofuran View Scheme
参考文献
Synthetic Communications, , vol. 17, # 15 p. 1845 - 1850
