(11S)-11-羟基二十碳-5,8,12,14-四烯酸合成路线 (共 2 条)
反应条件
sodium tetrahydroborate; Tris-HCl buffer; lipoxygenase; borate buffer
1.) 23 deg C, 3 h, 2.) MeOH, 30 min; Multistep reaction;
参考文献
Kato, Tadahiro; Watanabe, Tsutomu; Hirukawa, Toshifumi; Tomita, Norihiro; Namai, Tsuneo
Bulletin of the Chemical Society of Japan, 1996 , vol. 69, # 6 p. 1663 - 1666
反应条件
1: With Physcomitrella patens lipoxygenase PpLOX7; oxygen
pH=7.0; 0.5 h; aq. phosphate bufferEnzymatic reaction;
2: With sodium tetrahydroborate in methanol
0.5 h; enantiospecific reaction;
参考文献
Anterola, Aldwin; Goebel, Cornelia; Hornung, Ellen; Sellhorn, George; Feussner, Ivo; Grimes, Howard
Phytochemistry, 2009 , vol. 70, # 1 p. 45 - 57