6-苯甲酰基-2(3h)-苯噁唑酮合成路线 （共 18 条）
反应条件
1: 83 percent / K 10 montmorillonite / CH2Cl2 / 4 h / Heating
2: 86 percent / polyphosphoric acid / Irradiation; microwave (300 W), seven 30 sec-intervals over 15 min
View Scheme
参考文献
Poupaert, Jacques H.; Depreux, Patrick; McCurdy, Christopher R.
Monatshefte fur Chemie, 2003 , vol. 134, # 6 p. 823 - 830
反应条件
in acetonitrile
48 h; Irradiation;
参考文献
Ishida,S. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 1135 - 1138
反应条件
water
T=25°C; pH 10-11; Rate constant;
参考文献
Vigroux, Alain; Bergon, Michel; Zedde, Chantal
Journal of Medicinal Chemistry, 1995 , vol. 38, # 20 p. 3983 - 3994
反应条件
1: 80 percent / NaOH
2: 70 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature
View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
hydrogenchloride; ethanol; sodium
multistep reaction; other ω-chloro acid;
参考文献
Renard; Lesieur; Lespagnol; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 5 p. 453 - 456
反应条件
hydrogenchloride; ethanol; sodium
2.) DMF, reflux, 2 h, 3.) water; Yield given. Multistep reaction;
参考文献
Renard; Lesieur; Lespagnol; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 5 p. 453 - 456
反应条件
sodium tetrahydroborate in sodium hydroxide
2 h;
参考文献
Bonte; Lesieur; Lespagnol; et al.
European Journal of Medicinal Chemistry, 1974 , vol. 9, # 5 p. 497 - 500
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=125°C; 2 h;
参考文献
Ucar, Huseyin; Van Derpoorten, Kim; Cacciaguerra, Silvia; Spampinato, Santi; Stables, James P.; Depovere, Paul; Isa, Majed; Masereel, Bernard; Delarge, Jacques; Poupaert, Jacques H.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 7 p. 1138 - 1145
