2-疏基环己烯-1-羧酸乙酯合成路线 （共 4 条）
反应条件
1: 74 percent / Cl2(gas); aq. AcOH / 0.83 h / 15 °C 2: 78 percent / Et3N / ethyl acetate View Scheme
参考文献
Yamada, Masami; Ichikawa, Takashi; Ii, Masayuki; Sunamoto, Mie; Itoh, Katsumi; Tamura, Norikazu; Kitazaki, Tomoyuki
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7457 - 7467
反应条件
chlorine; acetic acid T=15°C; 0.833333 h;
参考文献
Yamada, Masami; Ichikawa, Takashi; Ii, Masayuki; Sunamoto, Mie; Itoh, Katsumi; Tamura, Norikazu; Kitazaki, Tomoyuki
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7457 - 7467
反应条件
1: 74 percent / Cl2(gas); aq. AcOH / 0.83 h / 15 °C 2: 78 percent / Et3N / ethyl acetate 3: 634 mg / HPLC-CHIRALPAK AD View Scheme
参考文献
Yamada, Masami; Ichikawa, Takashi; Ii, Masayuki; Sunamoto, Mie; Itoh, Katsumi; Tamura, Norikazu; Kitazaki, Tomoyuki
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7457 - 7467
反应条件
1: With hydrogen sulfide in ethanol
T=-50°C; 2 h;
2: With hydrogenchloride in ethanol
T=-20°C; 2 h;
3: With hydrogen sulfide in ethanol
T=-20°C; 16 h;
参考文献
Yamada, Masami; Ichikawa, Takashi; Ii, Masayuki; Sunamoto, Mie; Itoh, Katsumi; Tamura, Norikazu; Kitazaki, Tomoyuki
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7457 - 7467
