2-(4-甲氧苯基)乙胺合成路线 (共 112 条)
反应条件
hydrogenchloride; hydrogen; acetic acid; palladium on activated charcoal 1 h;
参考文献
Kalia, Narendra K.; Singh, Bikram; Sood, Ram P.
Journal of Natural Products, 1999 , vol. 62, # 2 p. 311 - 312
反应条件
lithium borohydride; tBuCH2CH2B(H)NiPr2 in tetrahydrofuran 18 h; Reflux;
参考文献
Haddenham, Dustin; Pasumansky, Lubov; DeSoto, Jamie; Eagon, Scott; Singaram, Bakthan
Journal of Organic Chemistry, 2009 , vol. 74, # 5 p. 1964 - 1970
反应条件
sodium hydroxide; bromine in water T=70 - 80°C; 0.25 h;
参考文献
Zhuangyu, Zhang; Yi, Pan; Hongwen, Hu; Tsi-yu, Kao
Synthetic Communications, 1990 , vol. 20, # 22 p. 3563 - 3574
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 1 h;
参考文献
Monguchi, Yasunari; Fujita, Yuki; Endo, Koichi; Takao, Shinobu; Yoshimura, Masatoshi; Takagi, Yukio; Maegawa, Tomohiro; Sajiki, Hironao
Chemistry - A European Journal, 2009 , vol. 15, # 4 p. 834 - 837
反应条件
samarium diiodide; water; isopropylamine in tetrahydrofuran
参考文献
Ankner, Tobias; Hilmersson, Goeran
Tetrahedron Letters, 2007 , vol. 48, # 32 p. 5707 - 5710
反应条件
water; triphenylphosphine in tetrahydrofuran T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 14 p. 4098 - 4115
反应条件
1: With chloro-trimethyl-silane; mischmetal in tetrahydrofuran 2 h; Inert atmosphereReflux; 2: With water in tetrahydrofuran 0.0833333 h; Alkaline conditions;
参考文献
Vellemaee, Eerold; Stepanov, Vladimir; Maeorg, Uno
Synthetic Communications, 2010 , vol. 40, # 22 p. 3397 - 3404
反应条件
hydrogen in isopropyl alcohol T=45 - 55°C; P=7500.75 - 9000.9 Torr;
参考文献
Organic Process Research and Development, , vol. 15, # 6 p. 1392 - 1395
反应条件
PPA T=145°C; 0.166667 h;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 12 p. 2208 - 2216
反应条件
1: pyridine / tetrahydrofuran / 20 °C 2: sodium azide / dimethylformamide / 20 °C 3: Ph3P; H2O / tetrahydrofuran / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 14 p. 4098 - 4115