2-(4-甲氧苯基)乙胺合成路线 （共 112 条）
参考文献
Journal of the Chemical Society, , vol. 95, p. 1722
反应条件
1: sodium acetate 2: sodium; xylene / Behandeln der Reaktionsloesung mit Methyljodid 3: hydriodic acid 4: concentrated hydrochloric acid / 170 °C View Scheme
参考文献
Walpole
Journal of the Chemical Society, 1910 , vol. 97, p. 946
反应条件
1: 99 percent / K2CO3 / tetrahydrofuran / 25 °C 2: 99 percent / LiAlH4 / tetrahydrofuran / Heating View Scheme
参考文献
Lagarias; Houghten; Rapoport
Journal of the American Chemical Society, 1978 , vol. 100, # 26 p. 8202 - 8209
反应条件
4-methyl-morpholine; lithium aluminium tetrahydride; N-ethyl-N,N-diisopropylamine; Wang resin 1.) 0 deg C, 2 h; room temp., overnight, 2.) DMF, room temp., overnight, 3.) THF, 60 deg C, 14 h; Yield given. Multistep reaction;
参考文献
Ho, Chih Y.; Kukla, Michael J.
Tetrahedron Letters, 1997 , vol. 38, # 16 p. 2799 - 2802
反应条件
anschliessend mit Dimethylsulfat und dann mit wss. Aethanol;
参考文献
Lee et al.
Barell-Festschr. <Basel 1946> S. 264,300
反应条件
2-(N,N-dimethylamino)-pyridine in pyridine
参考文献
Hoechst Aktiengesellschaft
Patent: US5574069 A1, 1996 ;
反应条件
1: α-phenylbenzeneacetic acid; 4-methyl-benzoic acid With thionyl chloride Combinatorial reaction / High throughput screening (HTS); 2: 2-(4-hydroxyphenyl)ethylamine; 1-adamantaneamine; 2-(4-methylphenyl)-ethylamine; 2-(3,4-dimethoxyphenyl)-ethylamine; phenethylamine; 2-(4-methoxy-phenyl)ethylamine; 3,4,5-trimethoxy-phenylamine; 2-(3-methoxy-phenyl)-ethylamine; 1-amino-2-(2-methoxyphenyl)ethane; (1R*,2S*)-2-methylamino-1-phenyl-1-propanol
参考文献
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
Patent: WO2005/44191 A2, 2005 ;
Location in patent: Figure 12 ;
反应条件
1: KOH / H2O / 0 deg C to r.t. 2: H2O / 0 °C 3: KOH / H2O / Ambient temperature 4: 2) HCl conc. / 1) CHCl3, reflux, 2) 90 deg C View Scheme
参考文献
Hirashima, Akinori; Yoshii, Yutaka; Eto, Morifusa
Bioscience, Biotechnology, and Biochemistry, 1992 , vol. 56, # 7 p. 1062 - 1065
参考文献
Waser; Brauchli
Helvetica Chimica Acta, 1924 , vol. 7, p. 755
反应条件
hydrogenchloride T=160 - 170°C;
参考文献
Barger; Walpole
Journal of the Chemical Society, 1909 , vol. 95, p. 1722
