2-(4-甲氧苯基)乙胺合成路线 （共 112 条）
反应条件
1: Et3N / tetrahydrofuran 2: PPA / 140 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 14 p. 1885 - 1888
反应条件
potassium carbonate in ethanol
参考文献
Schering Corporation
Patent: US2003/191130 A1, 2003 ;
US 20030191130 A1
反应条件
1: triethylamine / N,N-dimethyl-formamide / 1 h / 0 - 25 °C 2: trifluorormethanesulfonic acid / 29 h / 0 - 70 °C View Scheme
参考文献
Kurouchi, Hiroaki; Kawamoto, Kyoko; Sugimoto, Hiromichi; Nakamura, Satoshi; Otani, Yuko; Ohwada, Tomohiko
Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 9313 - 9328,16
反应条件
2: 1.) base, 2.) O-(2,4-dinitrophenyl)hydroxylamine 3: 82 percent / NCS / tetrahydrofuran / 16 h / Ambient temperature; Irradiation View Scheme
参考文献
Collazo, Luis R.; Guziec, Frank S.; Hu, Wei-Xiao Jr.; Pankayatselvan, Ratnadevi
Tetrahedron Letters, 1994 , vol. 35, # 43 p. 7911 - 7914
反应条件
in tetrahydrofuran
robotic synthesis; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Linclau, Bruno; Sing, Ashvani K.; Curran, Dennis P.
Journal of Organic Chemistry, 1999 , vol. 64, # 8 p. 2835 - 2842
反应条件
sulfuryl dichloride; acetic acid
T=20 - 30°C;
参考文献
Yu, Guixue; Mason, Helen J.; Galdi, Kim; Wu, Ximao; Cornelius, Lyndon; Zhao, Ning; Witkus, Michael; Ewing, William R.; Macor, John E.
Synthesis, 2003 , # 3 p. 403 - 407
反应条件
formic acid in water
3 h; Heating;
参考文献
Schroeder, Daniel R.; Stermitz, Frank R.
Tetrahedron, 1985 , vol. 41, # 19 p. 4309 - 4320
反应条件
2 h; Ambient temperature;
参考文献
Kirk, Kenneth L.; Nishida, Mazakazu; Fuji, Shozo; Kimoto, Hiroshi
Journal of Fluorine Chemistry, 1992 , vol. 59, # 2 p. 197 - 202
反应条件
pyridine; trifluoroacetic anhydride in tetrahydrofuran
参考文献
Fisons plc
Patent: US4657929 A1, 1987 ;
反应条件
trifluoroacetic anhydride in dichloromethane; toluene
参考文献
SmithKline Corporation
Patent: US4314944 A1, 1982 ;
Title/Abstract Full Text Show Details
SmithKline Beckman Corporation
Patent: US4414224 A1, 1983 ;
