反应条件
1.1: potassium phosphate / palladium diacetate; dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine / tetrahydrofuran / 8 h / 40 °C 2.1: sodium hydroxide / water; tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere 2.2: pH 6 / potassium phosphate buffer 3.1: potassium phosphate / palladium diacetate; dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine / tetrahydrofuran / 3 h / 20 °C View Scheme
参考文献
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; BURKE, Martin, D.; LI, Junqi; GILLIS, Eric, P.
Patent: WO2012/149182 A2, 2012 ;