4-(4-吡啶基)-1-哌啶羧酸叔丁酯合成路线 (共 3 条)
反应条件
1: With hydrogenchloride in 1,4-dioxane 1 h; 2: With sodium hydroxide; water in 1,4-dioxane
参考文献
SANOFI-AVENTIS
Patent: US2009/176775 A1, 2009 ;
Location in patent: Page/Page column 27-28 ;
反应条件
hydrogen; 5-palladium/activated carbon in methanol
T=25°C; P=2280.15 Torr; 1 h;
参考文献
SANOFI-AVENTIS
Patent: US2009/176775 A1, 2009 ;
Location in patent: Page/Page column 27 ;
反应条件
triethylamine in chloroform
T=20°C; 1 h;
参考文献
Jung, Dongju; Shimogawa, Hiroki; Kwon, Youngjoo; Mao, Qian; Sato, Shin-ichi; et al.
Journal of the American Chemical Society, 2009 , vol. 131, p. 4774 - 4782