alpha-(4-溴苯基)苄胺合成路线 （共 8 条）
反应条件
ammonia; [rhodium(I)(carbonyl)2(acetylacetonate)] in 1,4-dioxane; water T=80°C; 16 h;
参考文献
KANATA CHEMICAL TECHNOLOGIES INC.
Patent: WO2008/119161 A1, 2008 ;
Location in patent: Page/Page column 28; 36 ;
反应条件
ammonia; [Rh(acac)(η2-C2H4)2]; (S,S)-methyl-DuPhos in 1,4-dioxane; water T=80°C; 16 h;
参考文献
KANATA CHEMICAL TECHNOLOGIES INC.
Patent: WO2008/119162 A1, 2008 ;
Location in patent: Page/Page column 52; 64 ;
反应条件
potassium hydroxide in methanol 8 h; Reflux;
参考文献
MERCK SHARP and DOHME CORP.; ZHOU, Changyou; ZOU, Wuxin; HUA, Yuxia; DANG, Qun
Patent: WO2013/40790 A1, 2013 ;
Location in patent: Page/Page column 37 ;
反应条件
potassium hydroxide in methanol 8 h; Reflux;
参考文献
MERCK SHARP and DOHME CORP.; DANG, Qun; ZHOU, Changyou; ZOU, Wuxin; HUA, Yuxia
Patent: WO2013/43624 A1, 2013 ;
Location in patent: Page/Page column 37; 38 ;
反应条件
ammonium formate; sodium hydrogencarbonate in hydrogenchloride; water; ethyl acetate
反应条件
1: 24 h / 185 °C 2: potassium hydroxide / methanol / 8 h / |Reflux View Scheme
反应条件
sodium amalgam; acetic acid (+-)-4-bromo-benzhydrylamine;
参考文献
Bulletin de la Societe Chimique de France, , vol. <4>47, p. 289,299
反应条件
sodium amalgam; acetic acid (+-)-4-bromo-benzhydrylamine;
参考文献
Bulletin de la Societe Chimique de France, , vol. <4>47, p. 289,299
