[4-(苄基氨基-甲基)-苯基]-二甲基-胺合成路线 （共 5 条）
反应条件
4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran
T=25°C; 3 h; Inert atmosphere;
参考文献
Nador, Fabiana; Moglie, Yanina; Ciolino, Andres; Pierini, Adriana; Dorn, Viviana; Yus, Miguel; Alonso, Francisco; Radivoy, Gabriel
Tetrahedron Letters, 2012 , vol. 53, # 25 p. 3156 - 3160
反应条件
1: 2 h / 100 °C
2: sodium tetrahydroborate / methanol / 12 h
View Scheme
参考文献
Ouyang, Qin; Tong, Qin; Feng, Rentian; Myint, Kyaw-Zeyar; Yang, Peng; Xie, Xiang-Qun
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 4 p. 387 - 392
反应条件
1: With hydrogenchloride in diethyl ether
T=23°C; 1 h; Inert atmosphere;
2: With sodium hydrogencarbonate in methanol; water
T=23°C; 2 h; Inert atmosphere;
参考文献
Cheng, Chen; Brookhart, Maurice
Journal of the American Chemical Society, 2012 , vol. 134, # 28 p. 11304 - 11307
反应条件
ethanol; platinum
Hydrogenation;
参考文献
Hinman; Hamm
Journal of Organic Chemistry, 1958 , vol. 23, p. 529
反应条件
1.1: [Ir(μ-Cl)(cyclooctene)2]2; diethylesilane / benzene / 6 h / 23 °C / Inert atmosphere
2.1: hydrogenchloride / diethyl ether / 1 h / 23 °C / Inert atmosphere
2.2: 2 h / 23 °C / Inert atmosphere
View Scheme
参考文献
Cheng, Chen; Brookhart, Maurice
Journal of the American Chemical Society, 2012 , vol. 134, # 28 p. 11304 - 11307
