4-羟基-3-甲基-2-丙-2-烯基-环戊-2-烯-1-酮合成路线 （共 28 条）
反应条件
1: 62 percent / 10percent aq. NaOH / toluene / 5 h / -3 - -1 °C
2: H2 / Lindlar catalyst / methanol / 20 °C
View Scheme
参考文献
Matsuo; Fujita; Magara; et al.
Agricultural and Biological Chemistry, 1982 , vol. 46, # 7 p. 1911 - 1912
反应条件
2: 62 percent / 10percent aq. NaOH / toluene / 5 h / -3 - -1 °C
3: H2 / Lindlar catalyst / methanol / 20 °C
View Scheme
参考文献
Matsuo; Fujita; Magara; et al.
Agricultural and Biological Chemistry, 1982 , vol. 46, # 7 p. 1911 - 1912
反应条件
1: aq. HClO4
2: KOtBu
View Scheme
参考文献
Romanet,R.F.; Schlessinger,R.H.
Journal of the American Chemical Society, 1974 , vol. 96, # 11 p. 3701 - 3702
反应条件
sodium carbonate; Amberllite 122 (acidic form)
1.) dioxan, H2O, r.t., 3 h, 2.) reflux, 6 h; Yield given. Multistep reaction;
参考文献
Fujita, Yoshiji; Nakai, Takeshi
Synthesis, 1983 , # 12 p. 997 - 1000
反应条件
1: 93 percent / tetraethylammonium perchlorate / 4 h / Ambient temperature; platinum foil electrodes (18.7 mA/cm2)
2: 2.) Na2CO3 / 1.) Amberllite 122 (acidic form) / 1.) dioxan, H2O, r.t., 3 h, 2.) reflux, 6 h
View Scheme
参考文献
Fujita, Yoshiji; Nakai, Takeshi
Synthesis, 1983 , # 12 p. 997 - 1000
反应条件
sodium hydroxide in ethanol
参考文献
Farkas,J. et al.
Collection of Czechoslovak Chemical Communications, 1960 , vol. 25, p. 1824 - 1836
反应条件
1: 1.) NaH / 1.) DMF, RT, 2.) DMF, -5 deg C, 1 h
2: 2.) H2SO4 / 1.) methanol, -5 deg C, 2.) methanol, -5 deg C
3: 2.9 g / 1 M HCl / 1 h / 50 °C
4: 67 percent / EtONa / ethanol / 1 h / Ambient temperature
View Scheme
参考文献
Ono, Noboru; Tanabe, Yo; Tanikaga, Rikuhei; Kaji, Aritsune; Matsuo, Takashi
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 10 p. 3033 - 3034
反应条件
1: 2.) H2SO4 / 1.) methanol, -5 deg C, 2.) methanol, -5 deg C
2: 2.9 g / 1 M HCl / 1 h / 50 °C
3: 67 percent / EtONa / ethanol / 1 h / Ambient temperature
View Scheme
参考文献
Ono, Noboru; Tanabe, Yo; Tanikaga, Rikuhei; Kaji, Aritsune; Matsuo, Takashi
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 10 p. 3033 - 3034
反应条件
1: Et3N / benzene / 2 h / Heating
2: TsOH / 1 h
3: 1.) acid Ti(3+), Zn, NaHCO3, 2.) aq. NaOH / 1.) methanol, pH 3-4, room temperature, 2.) methanol, 5 deg C, 18 h
View Scheme
参考文献
Andersen, Soeren H.; Das, Nalin B.; Joergensen, Ruth D.; Kjeldsen, Gunhild; Knudsen, Jes S.; et al.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 1 p. 1 - 14
反应条件
1: silver nitrite
2: Et3N / benzene / 2 h / Heating
3: TsOH / 1 h
4: 1.) acid Ti(3+), Zn, NaHCO3, 2.) aq. NaOH / 1.) methanol, pH 3-4, room temperature, 2.) methanol, 5 deg C, 18 h
View Scheme
参考文献
Andersen, Soeren H.; Das, Nalin B.; Joergensen, Ruth D.; Kjeldsen, Gunhild; Knudsen, Jes S.; et al.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 1 p. 1 - 14
