thionyl chloride; N,N-dimethyl-formamide in dichloromethane 18 h;
参考文献
Viswanathan, Rajesh; Prabhakaran, Erode N.; Plotkin, Michael A.; Johnston, Jeffrey N.
Journal of the American Chemical Society, 2003 , vol. 125, # 1 p. 163 - 168
ELI LILLY AND COMPANY; HIPSKIND, Philip Arthur; STEPHENSON, Gregory Alan
Patent: US2013/29972 A1, 2013 ;
Location in patent: Paragraph 0031-0032 ;
US 20130029972 A1
1: methyllithium With copper(l) iodide in diethyl ether; Petroleum ether 0.0833333 h; cooling; 2: 2-(2-bromophenyl)acetyl chloride in diethyl ether; Petroleum ether T=-78°C; 0.5 h; Further stages.;
参考文献
Viswanathan, Rajesh; Prabhakaran, Erode N.; Plotkin, Michael A.; Johnston, Jeffrey N.
Journal of the American Chemical Society, 2003 , vol. 125, # 1 p. 163 - 168