N-(苄氧羰基)-L-酪氨酸苄酯合成路线 （共 15 条）
反应条件
in dichloromethane T=-40°C; 2 h;
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7529 - 7530
反应条件
triethylamine in dichloromethane
参考文献
Fretz, Heinz
Tetrahedron Letters, 1996 , vol. 37, # 47 p. 8475 - 8478
反应条件
1: 99.8 percent / triethylamine / CH2Cl2 / 28 h / 0 - 20 °C 2: 58 percent / Et3N / [PdCl2(PPh3)2] / dioxane / Heating 3: NaIO4; NH4OAc / acetone; H2O / 48 h / 20 °C 4: 207 mg / aq. NaOH / 1 h 5: 63 percent / hydrogen; aq. HCl / Pd(OH)2/C / ethanol / 19 h / 20 °C View Scheme
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 1 p. 231 - 235
反应条件
1: 1.) NaH / 1) DMF, rt, 40 min; 2) DMF, overnight 2: 91 percent / H2 / Pd/C / methanol / 2068.6 Torr / Ambient temperature 3: 87 percent / KHCO3 / dioxane; H2O / Ambient temperature View Scheme
参考文献
Burke Jr., Terrence R.; Yao, Zhu-Jun; Zhao, He; Milne, George W. A.; Wu, Li; Zhang, Zhong-Yin; Voigt, Johannes H.
Tetrahedron, 1998 , vol. 54, # 34 p. 9981 - 9994
反应条件
1: 99.8 percent / triethylamine / CH2Cl2 / 28 h / 0 - 20 °C
2: 58 percent / Et3N / [PdCl2(PPh3)2] / dioxane / Heating
3: NaIO4; NH4OAc / acetone; H2O / 48 h / 20 °C
View Scheme
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 1 p. 231 - 235
