反应条件
1: 1) TEA; 2) NaBH4 / 1) room temp., 1 h; 2) room temp. 2h
2: 46.4 percent / hydrogen / 10percent Pd-C / H2O / Ambient temperature
3: 54.5 percent / TEA / acetonitrile / 4 h / Ambient temperature
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; GRAUERT, Matthias; BISCHOFF, Daniel; DAHMANN, Georg; KUELZER, Raimund; RUDOLF, Klaus; WELLENZOHN, Bernd
Patent: WO2013/83741 A1, 2013 ;