反应条件
1: piperidine; pyridine / 12 h / 85 °C
2: potassium carbonate / N,N-dimethyl-formamide / 20 °C
3: iron; ammonium chloride / tetrahydrofuran; ethanol; water / 1 h / 85 °C
4: triethylamine / dichloromethane / 0 - 20 °C
5: potassium tert-butylate / dimethyl sulfoxide / 1 h / 15 °C
6: trichlorophosphate / acetonitrile / Inert atmosphere; Reflux
7: hydrogenchloride / water / 6 h / Reflux
View Scheme
参考文献
Ni, Lijun; Li, Ziyuan; Wu, Fan; Xu, Jinyi; Wu, Xiaoming; Kong, Lingyi; Yao, Hequan
Tetrahedron Letters, 2012 , vol. 53, # 10 p. 1271 - 1274