2-(2-羟基乙氧基)-苯甲酸合成路线 (共 4 条)
反应条件
hydrogenchloride
24 h; Heating;
参考文献
Jones, Paul R.; Rothenberger, Scott D.
Journal of Organic Chemistry, 1986 , vol. 51, # 15 p. 3016 - 3023
反应条件
1: 75 percent / 30percent NH4OH / 1 h / Ambient temperature
2: 67 percent / 20percent HCl / 24 h / Heating
View Scheme
参考文献
Jones, Paul R.; Rothenberger, Scott D.
Journal of Organic Chemistry, 1986 , vol. 51, # 15 p. 3016 - 3023
反应条件
n-butyllithium
1.) THF, methylcyclohexane, -65 deg C to rt, 2.) THF, methylcyclohexane, -65 deg C to rt; Yield givenMultistep reaction;
参考文献
Salteris, Constantinos S.; Kostas, Ioannis D.; Micha-Screttas, Maria; Heropoulos, George A.; Screttas, Constantinos G.; Terzis, Aris
Journal of Organic Chemistry, 1999 , vol. 64, # 15 p. 5589 - 5592
反应条件
sodium hydroxide; chlorobenzene
Erwaermen des Reaktionsprodukts mit wss. NaOH;
参考文献
Gen. Aniline and Film Corp.
Patent: US2696498 , 1951 ;