2-(4-甲基苯基)-2-氧代乙酸乙酯合成路线 （共 23 条）
参考文献
Auwers
Chemische Berichte, 1911 , vol. 44, p. 599
参考文献
Kiesewetter, Dale O.; Carson, Richard E.; Jagoda, Elaine M.; Endres, Christopher J.; Der, Margaret G.; Herscovitch, Peter; Eckelman, William C.
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 8 p. 1555 - 1567
反应条件
1.1: Mg / diethyl ether / 1 h / 20 °C
1.2: 4.88 g / diethyl ether / 5 h / -78 - 0 °C
2.1: polyphosphoric acid; phosphoric acid / 1 h / 75 - 80 °C
3.1: KOH / propan-2-ol / 1.25 h / Heating
4.1: 0.086 g / oxygen; KOH / propan-2-ol / 2.5 h
View Scheme
参考文献
Levy, Amalia; Rakowitz, Amber; Mills, Nancy S.
Journal of Organic Chemistry, 2003 , vol. 68, # 10 p. 3990 - 3998
