反应条件
1: 1.) CH3ONa / 1.) DMF, RT, 1 h, 2.) DMF, 120 deg C, 6 h 2: 1.) CuCl2*2H2O, 2.) NaBH4 / 1.) ethanol, 0 deg C, 1 h, 2.) ethanol, 0 deg C 45 min. 3: 94 percent / 12N HCl / 0 °C 4: 1N HCl / 3 h / Heating 5: 90 percent / Et3N / 1,2-dimethoxy-ethane / 15 h / Ambient temperature View Scheme
参考文献
Heterocycles, , vol. 20, # 9 p. 1731 - 1735
