3,4-二氢-2(1H)-喹啉酮合成路线 （共 181 条）
反应条件
trifluorormethanesulfonic acid in toluene T=150°C; 0.25 h; Microwave irradiation;
参考文献
Rombouts, Frederik; Franken, Dennis; Martinez-Lamenca, Carolina; Braeken, Mirielle; Zavattaro, Chiara; Chen, Jinsheng; Trabanco, Andres A.
Tetrahedron Letters, 2010 , vol. 51, # 37 p. 4815 - 4818
反应条件
potassium hydroxide; water Bei der elektrochemischen Reduktion an Nickel-Kathoden;
参考文献
Helvetica Chimica Acta, , vol. 32, p. 1278,1281
反应条件
triethylaluminum; pyridine; bis(acetylacetonate)nickel(II) in tetrahydrofuran; toluene T=80 - 100°C; 5 h;
参考文献
Journal of Chemical Research, Miniprint, , # 2 p. 646 - 666
反应条件
1: With hydrogenchloride; sodium azide in water T=0°C; Schmidt reaction; 0.5 h; 2: With potassium carbonate in water pH=9; Cooling with ice;
参考文献
ChemMedChem, , vol. 5, # 8 p. 1300 - 1317
反应条件
Raney nickel W-2 in ethanol 0.5 h; Heating;
参考文献
Kikugawa, Yasuo; Nagashima, Akira; Sakamoto, Takeshi; Miyazawa, Etsuko; Shiiya, Megumi
Journal of Organic Chemistry, 2003 , vol. 68, # 17 p. 6739 - 6744
反应条件
zirconium dichloride in dichloromethane T=10 - 20°C; Beckmann rearrangement; 1 h;
参考文献
Torisawa, Yasuhiro; Nishi, Takao; Minamikawa, Jun-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 10 p. 2205 - 2209
反应条件
palladium in ethanol
参考文献
US5478842 A1, ;
US 5478842 A
反应条件
1: With palladium diacetate in 1,4-dioxane T=50°C; Heck reduction-cyclisation reaction; 12 h; 2: With hydrogen; palladium diacetate; carbon in 1,4-dioxane T=50°C; Heck reduction-cyclisation reaction; 24 h;
参考文献
Felpin, Francois-Xavier; Coste, Jerome; Zakri, Cecile; Fouquet, Eric
Chemistry - A European Journal, 2009 , vol. 15, # 29 p. 7238 - 7245
反应条件
anhydrous iron chloride; potassium carbonate; N-methyl-2-(methylamino)ethylamine in toluene T=135°C; 24 h; Inert atmosphere;
参考文献
Correa, Arkaitz; Elmore, Simon; Bolm, Carsten
Chemistry - A European Journal, 2008 , vol. 14, # 12 p. 3527 - 3529
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in dimethyl sulfoxide T=120°C;
参考文献
Zhou, Wang; Zhang, Liangren; Jiao, Ning
Tetrahedron, 2009 , vol. 65, # 10 p. 1982 - 1987
