1-呋喃-3-基-4-甲基-1-戊酮合成路线 （共 9 条）
反应条件
copper(l) chloride in tetrahydrofuran
-10 deg C to r.t., then 20 min;
参考文献
Cahiez; Chavant; Metais
Tetrahedron Letters, 1992 , vol. 33, # 36 p. 5245 - 5248
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
12 h; Ambient temperature;
参考文献
Bailey
Synthesis, 1991 , # 3 p. 242 - 243
反应条件
dihydrogen peroxide; lithium tert-butylate
1.) diethyl ether, r.t., 1 h, 2.) diethyl ether, pH 8 phosphate buffer, 12 h; Yield given. Multistep reaction;
参考文献
Brown,H.C.; Srebnik,M.; Bakshi,R.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 5420
反应条件
hydrogenchloride in tetrahydrofuran
Ambient temperature; Yield given;
参考文献
Katritzky, Alan R.; Lang, Hengyuan; Wang, Zuoquan; Zhang, Zhongxing; Song, Huimin
Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7619 - 7624
反应条件
1: 71 percent / H2SO4 / ethanol; tetrahydrofuran / 3 h / Ambient temperature
2: n-BuLi / tetrahydrofuran; cyclohexane / 1.) -78 deg C, 2.) -78 deg C, 2 min
3: aq. HCl / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
Katritzky, Alan R.; Lang, Hengyuan; Wang, Zuoquan; Zhang, Zhongxing; Song, Huimin
Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7619 - 7624
反应条件
1: n-BuLi / tetrahydrofuran; cyclohexane / 1.) -78 deg C, 2.) -78 deg C, 2 min
2: aq. HCl / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
Katritzky, Alan R.; Lang, Hengyuan; Wang, Zuoquan; Zhang, Zhongxing; Song, Huimin
Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7619 - 7624
反应条件
1: n-BuLi / tetrahydrofuran; cyclohexane / 1.) -78 deg C, 2.) -78 deg C, 2 min
2: aq. HCl / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
Katritzky, Alan R.; Lang, Hengyuan; Wang, Zuoquan; Zhang, Zhongxing; Song, Huimin
Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7619 - 7624
反应条件
lithium tetrachloromanganate(II); iron (III) acetylacetonate
1) THF, -80 deg C, 30 min, 2) -70 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Cahiez; Chavant; Metais
Tetrahedron Letters, 1992 , vol. 33, # 36 p. 5245 - 5248
参考文献
Matsuura
Bulletin of the Chemical Society of Japan, 1957 , vol. 30, p. 430
