3,4-二甲氧基-N,N-二甲基-1-菲乙胺合成路线 （共 16 条）
反应条件
lithium aluminium tetrahydride
参考文献
Seijas, Julio A.; Lera, Angel R. de; Villaverde, M. Carmen; Castedo, Luis
Journal of the Chemical Society, Chemical Communications, 1985 , # 12 p. 839 - 840
反应条件
sodium tetrahydroborate in methanol
24 h;
参考文献
Hufford; Sharma; Oguntimein
Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 10 p. 1180 - 1183
反应条件
1: 81 percent / methanol; H2O / 15 h / Ambient temperature
2: 68 percent / LiAlH4 / tetrahydrofuran / 5 h / Heating
View Scheme
参考文献
Estevez, Juan C.; Villaverde, M. Carmen; Estevez, Ramon J.; Castedo, Luis
Tetrahedron, 1993 , vol. 49, # 13 p. 2783 - 2790
反应条件
1: zinc powder, 20 percent aq. sulphuric acid / 3.5 h
2: sodium borohydride / H2O
View Scheme
参考文献
Lu, Sheng-Teh; Wu, Yang-Chang
Heterocycles, 1985 , vol. 23, # 12 p. 3085 - 3094
反应条件
1: 38 percent / CHCl3 / 3 h / Heating
2: zinc powder, 20 percent aq. sulphuric acid / 3.5 h
3: sodium borohydride / H2O
View Scheme
参考文献
Lu, Sheng-Teh; Wu, Yang-Chang
Heterocycles, 1985 , vol. 23, # 12 p. 3085 - 3094
反应条件
1: 32 percent / m-CPBA / CHCl3 / 1 h / Ambient temperature
2: 38 percent / CHCl3 / 3 h / Heating
3: zinc powder, 20 percent aq. sulphuric acid / 3.5 h
4: sodium borohydride / H2O
View Scheme
参考文献
Lu, Sheng-Teh; Wu, Yang-Chang
Heterocycles, 1985 , vol. 23, # 12 p. 3085 - 3094
反应条件
sodium tetrahydroborate in water
参考文献
Lu, Sheng-Teh; Wu, Yang-Chang
Heterocycles, 1985 , vol. 23, # 12 p. 3085 - 3094
反应条件
1: CH2Cl2 / Ambient temperature
2: 1.) NaH / 1.) THF, r.t., 2.) r.t.
3: 68 percent / LAH, AlCl3 / tetrahydrofuran / Heating
View Scheme
参考文献
Estevez; Carmen Villaverde; Seijas; Castedo
Canadian Journal of Chemistry, 1990 , vol. 68, # 6 p. 964 - 968
反应条件
1: LAH / tetrahydrofuran / 1.) reflux, 2.) r.t.
2: CH2Cl2 / Ambient temperature
3: 1.) NaH / 1.) THF, r.t., 2.) r.t.
4: 68 percent / LAH, AlCl3 / tetrahydrofuran / Heating
View Scheme
参考文献
Estevez; Carmen Villaverde; Seijas; Castedo
Canadian Journal of Chemistry, 1990 , vol. 68, # 6 p. 964 - 968
反应条件
1: 65 percent / aq. ammonia / methanol / Ambient temperature
2: LAH / tetrahydrofuran / 1.) reflux, 2.) r.t.
3: CH2Cl2 / Ambient temperature
4: 1.) NaH / 1.) THF, r.t., 2.) r.t.
5: 68 percent / LAH, AlCl3 / tetrahydrofuran / Heating
View Scheme
参考文献
Estevez; Carmen Villaverde; Seijas; Castedo
Canadian Journal of Chemistry, 1990 , vol. 68, # 6 p. 964 - 968
