hydrogenchloride in water 12 h; Reflux;

diethyl ether T=-40°C;

1: N,N-dimethyl-formamide / 2 h / Reflux 2: hydrogenchloride / water / 12 h / Reflux View Scheme

1: oxalyl dichloride; N,N-dimethyl-formamide 2: 4-(N,N-dimethlyamino)pyridine; trichloromonobromomethane; Fonderma / 4 h / Reflux 3: N,N-dimethyl-formamide / 2 h / Reflux 4: hydrogenchloride / water / 12 h / Reflux View Scheme

1: 4-(N,N-dimethlyamino)pyridine; trichloromonobromomethane; Fonderma / 4 h / Reflux 2: N,N-dimethyl-formamide / 2 h / Reflux 3: hydrogenchloride / water / 12 h / Reflux View Scheme