反应条件
1: 91 percent / p-TsOH*H2O / CH2Cl2 / 3 h / 25 °C 2: 1) n-BuLi / 1) THF, HMPA, 0 deg C, 10 min, 2) rt, overnight 3: 93 percent / H2, quinoline / Pd/C/CaCO3 / hexane / 760 Torr 4: 77 percent / p-TsOH*H2O / methanol / 2 h / Ambient temperature 5: 88 percent / pyridinium chlorochromate / CH2Cl2 / 1.5 h / Ambient temperature 6: 1) LDA / 1) THF, -10 deg C, 10 min, 2) -78 deg C -> 25 deg C 7: 55 percent / CH2Cl2 / Ambient temperature View Scheme
参考文献
Ahn, Jong-Woong; Ahn, Mi-Ja; Zee, Ok-Pyo; Kim, Eun-Joo; Lee, Sueg-Geun; et al.
Phytochemistry (Elsevier), 1992 , vol. 31, # 10 p. 3609 - 3612
