1-羟基-8-甲氧基-9,10-蒽醌合成路线 （共 30 条）
反应条件
hydrogenchloride; potassium carbonate
1) acetone, 70 deg C, 8 h 2) room temp.; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Cava, Michael P.; Ahmed, Zareen; Benfaremo, Nicholas; Murphy, Raymond A.; O'Malley, Gerard J.
Tetrahedron, 1984 , vol. 40, # 22 p. 4767 - 4776
反应条件
in benzene
Inert atmospherePhotolysis;
参考文献
Sarma, Saurav J.; Jones, Paul B.
Journal of Organic Chemistry, 2010 , vol. 75, # 11 p. 3806 - 3813
参考文献
Auterhoff; Oettmeier
Archiv der Pharmazie, 1975 , vol. 308, # 10 p. 732 - 736
反应条件
1: 1.) 5percent NaOH, Na2S2O4 / 1.) MeOH, water, 70 deg C, 15 min, 2.) MeOH, water, 90 deg C, overnight
2: 82 percent / HBr / acetic acid / 3 h / Heating
View Scheme
参考文献
Zembower; Kam; Powers; Zalkow
Journal of Medicinal Chemistry, 1992 , vol. 35, # 9 p. 1597 - 1605
反应条件
potassium carbonate; potassium iodide in acetone
48 h; Heating;
参考文献
Zembower; Kam; Powers; Zalkow
Journal of Medicinal Chemistry, 1992 , vol. 35, # 9 p. 1597 - 1605
反应条件
1: 95 percent / K2CO3, KI / acetone / 48 h / Heating
2: 64 percent / Na2S2O4, NaOH / dimethylformamide; H2O / 2 h / 70 °C
View Scheme
参考文献
Takahashi; Terashima
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 12 p. 4539 - 4544
反应条件
1: 95 percent / K2CO3, KI / acetone / 48 h / Heating
2: 64 percent / Na2S2O4, NaOH / dimethylformamide; H2O / 2 h / 70 °C
3: 72 percent / K2CO3 / acetone / 21 h / Heating
View Scheme
参考文献
Takahashi; Terashima
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 12 p. 4539 - 4544
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
T=0 - 25°C;
参考文献
Cava, Michael P.; Ahmed, Zareen; Benfaremo, Nicholas; Murphy, Raymond A.; O'Malley, Gerard J.
Tetrahedron, 1984 , vol. 40, # 22 p. 4767 - 4776
反应条件
potassium carbonate in acetone
Reflux;
参考文献
Li, Yang; Cao, Rui; Lippard, Stephen J.
Organic Letters, 2011 , vol. 13, # 19 p. 5052 - 5055
反应条件
sodium hydroxide; sodium dithionite
1) THF/CH3OH, 10 min.; 2) H20, 12 h, room temp.; Yield given. Multistep reaction;
参考文献
Krohn; Muller; Priyono; et al.
1984 , vol. 1984, # 2 p. 306 - 318
