1: With trichlorophosphate in dichloromethane 2 h; Inert atmosphereReflux; 2: With sodium hydrogencarbonate in water T=20°C; 15 h;
参考文献
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; Cui, Zhengrong; Lansakara-P., Dharmika S. P.; Sandoval, Michael A.
Patent: US2013/131008 A1, 2013 ;
Location in patent: Paragraph 0142 ;
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反应条件
1: trans-4-isopropylcyclohexanecarboxylic acid; triethylamine With pivaloyl chloride in acetone T=5 - 20°C; 3.5 h; 2: (D)-phenylalanine methyl ester hydrochloride in acetone T=20°C; Product distribution / selectivity;
