1: 4-chlorobenzaldehyde; cyanoacetic acid ethyl ester With 2,6-dimethyl-1,4-dihydropyrimidine-3,5-dicarboxylic acid diethyl ester; L-proline in ethanol T=25°C; Knoevenagel/hydrogenation reaction; 2: methyl iodide With potassium carbonate in ethanol T=25°C;