3-苯基-1,2,4-噁二唑-5-甲醇合成路线 （共 5 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide; toluene
8 h; Dean-StarkReflux;
参考文献
Neves Filho, Ricardo A. W.; Da Silva-Alves, Diana C. B.; Dos Anjos, Janaina V.; Srivastava, Rajendra M.
Synthetic Communications, 2013 , vol. 43, # 19 p. 2596 - 2602
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane in acetic acid
Heating;
参考文献
Palazzo,G. et al.
Journal of Heterocyclic Chemistry, 1979 , vol. 16, p. 1469 - 1475
反应条件
potassium hydroxide in ethanol
Heating;
参考文献
Palazzo,G.; Silvestrini,B.
Bollettino Chimico Farmaceutico, 1962 , vol. 101, p. 251 - 258
反应条件
1.1: sodium hydroxide; water / tetrahydrofuran / 1 h / 20 °C
2.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 1 h / 0 - 20 °C
2.2: 15 h / 20 °C
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran; water / 0.02 h / 20 °C
View Scheme
参考文献
Otaka, Hiromichi; Ikeda, Junya; Tanaka, Daisuke; Tobe, Masanori
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 979 - 981
反应条件
1.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 1 h / 0 - 20 °C
1.2: 15 h / 20 °C
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran; water / 0.02 h / 20 °C
View Scheme
参考文献
Otaka, Hiromichi; Ikeda, Junya; Tanaka, Daisuke; Tobe, Masanori
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 979 - 981
