2-(p-羟基苯基)-2-苯基-苯乙酮合成路线 （共 8 条）
参考文献
Japp; Wadsworth
Journal of the Chemical Society, 1890 , vol. 57, p. 965
反应条件
copper(l) iodide; 2-acetyl-1-cyclohexanone; caesium carbonate in tert-butyl alcohol
T=70°C; 24 h; Inert atmosphere;
参考文献
Danoun, Gregory; Tlili, Anis; Monnier, Florian; Taillefer, Marc
Angewandte Chemie - International Edition, 2012 , vol. 51, # 51 p. 12815 - 12819
Angew. Chem., 2012 , vol. 124, # 51 p. 12987 - 12991,5
反应条件
hydrogen bromide in acetic acid
6 h; Heating;
参考文献
Stanciuc; Balaban
Journal of Pharmaceutical Sciences, 1993 , vol. 82, # 9 p. 927 - 933
反应条件
1: 81 percent / 89percent phosphoric acid / 8 h / 135 - 140 °C
2: 77.5 percent / 48percent hydrobromic acid / acetic acid / 6 h / Heating
View Scheme
参考文献
Stanciuc; Balaban
Journal of Pharmaceutical Sciences, 1993 , vol. 82, # 9 p. 927 - 933
反应条件
1: 81 percent / 89percent phosphoric acid / 8 h / 135 - 140 °C
2: 77.5 percent / 48percent hydrobromic acid / acetic acid / 6 h / Heating
View Scheme
参考文献
Stanciuc; Balaban
Journal of Pharmaceutical Sciences, 1993 , vol. 82, # 9 p. 927 - 933
反应条件
sulfuric acid
Behandeln des Reaktionsprodukts mit Wasser und Erhitzen mit konz.Salzsaeure bei 200grad;
参考文献
Japp; Wadsworth
Journal of the Chemical Society, 1890 , vol. 57, p. 965
反应条件
trifluoroacetic acid
3 h; Heating;
参考文献
Montfort, Bernard; Vebrel, Joel; Laude, Bernard; Charpentier-Morize, Micheline
Bulletin de la Societe Chimique de France, 1983 , vol. 2, # 7-8 p. 245 - 248
参考文献
Japp; Wadsworth
Journal of the Chemical Society, 1890 , vol. 57, p. 965
