6,11-二氢-11-氧二苯并[b,e]氧杂卓-2-乙酸合成路线 （共 11 条）
反应条件
1.1: thionyl chloride / dichloromethane / 5 h / Reflux 2.1: dichloromethane / 0 - 20 °C / pH 9.5 - 10 3.1: tetrahydrofuran / 1 h / 0 - 5 °C 3.2: 0 - 35 °C 3.3: 0 - 5 °C / pH 9 - 10 4.1: hydrogenchloride; water / 90 - 95 °C 4.2: 0.5 h / 10 - 15 °C / pH 6.8 - 7.2 5.1: hydrogenchloride / chlorobenzene / 5 h / 80 - 85 °C View Scheme
参考文献
Sumitomo Chemical Company, Limited
Patent: EP2385045 A1, 2011 ;
