7-氟-3,4-二氢-3-氧代-2-喹喔啉羧酸乙酯合成路线 （共 3 条）
反应条件
phosphorus tribromide in N,N-dimethyl-formamide
T=20°C; 1.5 h;
参考文献
Takano, Yasuo; Shiga, Futoshi; Asano, Jun; Ando, Naoki; Uchiki, Hideharu; Fukuchi, Kazunori; Anraku, Tsuyosi
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 20 p. 5841 - 5863
反应条件
1: 88 percent / toluene / 24 h / Heating
2: 31 percent / potassium tert-butoxide / dimethylformamide / 1.5 h / 0 °C
3: 75 percent / PBr3 / dimethylformamide / 1.5 h / 20 °C
View Scheme
参考文献
Takano, Yasuo; Shiga, Futoshi; Asano, Jun; Ando, Naoki; Uchiki, Hideharu; Fukuchi, Kazunori; Anraku, Tsuyosi
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 20 p. 5841 - 5863
反应条件
in ethanol
2 h; Heating;
参考文献
Sanna, Paolo; Carta, Antonio; Loriga, Mario; Zanetti, Stefania; Sechi, Leonardo
Farmaco, 1998 , vol. 53, # 7 p. 455 - 461
