1: (4-nitro-phenyl)-methanol With [2,2']bipyridinyl; copper(l) chloride in N,N-dimethyl-formamide T=20°C; 24 h; 2: acetone With Tris-HCl in water; N,N-dimethyl-formamide T=0°C; direct asymmetric aldol reaction; pH=7.8; 24 h; optical yield given as percent ee;
1: With potassium tert-butylate in tetrahydrofuran T=20°C; 0.0833333 h; 2: With 3,3-dimethyldioxirane in tetrahydrofuran; acetone T=20°C; 0.0833333 h; Further stages.;
参考文献
Makosza; Adam; Zhao; Surowiec
Journal of Organic Chemistry, 2001 , vol. 66, # 15 p. 5022 - 5026
