反应条件
1: 1.) KOH / 1.) acetone, reflux, 3 h; 2.) DMF, reflux, 10 h
2: 70 percent / polyphosphoric acid / 0.33 h / 120 °C
3: 0.1N NaOH / ethanol / Ambient temperature
View Scheme
参考文献
Gilis; Haemers; Bollaert
European Journal of Medicinal Chemistry, 1978 , vol. 13, # 3 p. 265 - 269