sodium hydroxide in ethanol Ambient temperature;

1: 1.) KOH / 1.) acetone, reflux, 3 h; 2.) DMF, reflux, 10 h 2: 1.5 g / Br2 / CHCl3; pyridine / 0.25 h / Ambient temperature 3: 75 percent / polyphosphoric acid / 0.33 h / 120 °C 4: 0.1N NaOH / ethanol / Ambient temperature View Scheme

1: 1.5 g / Br2 / CHCl3; pyridine / 0.25 h / Ambient temperature 2: 75 percent / polyphosphoric acid / 0.33 h / 120 °C 3: 0.1N NaOH / ethanol / Ambient temperature View Scheme

1: 75 percent / polyphosphoric acid / 0.33 h / 120 °C 2: 0.1N NaOH / ethanol / Ambient temperature View Scheme