戊腈,4-甲基-2-苯基-,合成路线 （共 5 条）
反应条件
oxygen; cyclohexyl(iPr)NLi in dimethyl sulfoxide 16 h; Ambient temperature; Further byproducts given;
参考文献
Kulp, Stuart S.; McGee, Michael J.
Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4097 - 4098
参考文献
Bodroux; Taboury
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1910 , vol. 150, p. 532
Bulletin de la Societe Chimique de France, 1910 , vol. <4> 7, p. 667
反应条件
1: phenylacetonitrile With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; 0.75 h;
2: 2-methyl-1-bromopropane in tetrahydrofuran; hexane
T=-78 - 20°C;
参考文献
Mermerian, Ara H.; Fu, Gregory C.
Angewandte Chemie - International Edition, 2005 , vol. 44, # 6 p. 949 - 952
反应条件
ruthenium-grafted hydrotalcite
T=180°C; 20 h;
参考文献
Motokura, Ken; Nishimura, Daisuke; Mori, Kohsuke; Mizugaki, Tomoo; Ebitani, Kohki; Kaneda, Kiyotomi
Journal of the American Chemical Society, 2004 , vol. 126, # 18 p. 5662 - 5663
反应条件
sodium amide in toluene; benzene
T=80°C; 1 h;
参考文献
Hartmann, Rolf W.; Batzl, Christine
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1362 - 1369
