1.1: hydrogen; 4-methyl-morpholine / platinum on carbon / 4 h / Inert atmosphere 2.1: sodium hydrogencarbonate / dichloromethane; water / 1.5 h / 0 °C 3.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C 3.2: 20 °C 4.1: isobutyl chloroformate / acetonitrile / 20 °C 5.1: potassium carbonate / N,N-dimethyl-formamide / 50 °C View Scheme

sodium hydroxide in 1,4-dioxane; water T=20°C; 0.25 h;

ethanol T=100°C;

hydrogenchloride; tin(ll) chloride