2-(2-丙炔氧基)苯羧酸合成路线 (共 6 条)
反应条件
potassium hydroxide; water in methanol T=20°C; Hydrolysis; 24 h;
参考文献
Chaudhuri, Gopeswar; Kundu, Nitya G.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 5 p. 775 - 779
反应条件
1: With lithium hydroxide hydrate in tetrahydrofuran; methanol; water T=0 - 20°C; 2: in tetrahydrofuran; methanol; water
参考文献
New Journal of Chemistry, , vol. 34, # 11 p. 2662 - 2670
反应条件
1: 74 percent / K2CO3 / acetone; toluene / 24 h / Heating 2: 73 percent / H2O, KOH / ethanol / 25 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 9 p. 1219 - 1223
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 0 °C 1.2: 0 - 20 °C 2.1: lithium hydroxide hydrate / tetrahydrofuran; methanol; water / 0 - 20 °C 2.2: Amberlite IR120(H+) View Scheme
参考文献
New Journal of Chemistry, , vol. 34, # 11 p. 2662 - 2670
反应条件
1: 2-O-(prop-2-ynyl) salicylic acid With sodium in methanol Salt formation; 0.0833333 h; 2: propargyl bromide; 2-hydroxybenzoic acid methyl ester With potassium carbonate in acetone Alkylation; 16 h; Heating; Further stages.;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 5 p. 775 - 779
参考文献
Pinho Melo, Teresa M. V.; Barbosa, Dalia M.; Ramos, Paulo J. R. S.; Rocha Gonsalves, Antonio M.; Gilchrist, Thomas L.; Beja, Ana M.; Paixaeo, Jose A.; Silva, Manuela R.; Veiga, Luiz Alte Da
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 9 p. 1219 - 1223