1: glycyl-glycyl-glycine With sodium hydroxide in water
T=0 - 5°C; pH=9 - 10.5; ice salt bath;
2: 2-methyl-acryloyl chloride in water
T=0 - 20°C; pH=9 - 10.5;
3: With nitric acid in water
参考文献
Access Pharmaceuticals, Inc.
Patent: US2011/286958 A1, 2011 ;
Location in patent: Page/Page column 1 ;