反应条件
1: 88 percent / benzene / 17 h / Heating
2: 1.) LiNEt2 / 1.) HMPT, benzene, THF, -45 deg C, 1.5 h, 2.) -45 deg C, 30 min; room temp., overnight
3: 10percent aq. HCl / hexamethylphosphoric acid triamide; benzene; tetrahydrofuran / 11.5 h / Heating
4: 1.) O3, 2.) Me2S / 1.) CH2Cl2, -60 deg C, 2.) -60 deg C, then room temp.
5: 89 percent / 1percent aq. NaOH / diethyl ether / 72 h / Ambient temperature
View Scheme
参考文献
Geraghty, Niall W. A.; Morris, Noreen M.
Synthesis, 1989 , # 8 p. 603 - 607
