5’-O-Trityl-3’-β-hydroxythymidine合成路线 （共 23 条）
反应条件
water; sodium hydroxide in ethanol 2 h; Reflux;
参考文献
Srivastav, Naveen C.; Shakya, Neeraj; Mak, Michelle; Agrawal, Babita; Tyrrell, D. Lorne; Kumar, Rakesh
Journal of Medicinal Chemistry, 2010 , vol. 53, # 19 p. 7156 - 7166
反应条件
sodium hydroxide in ethanol 1 h; Heating;
参考文献
Wilson, I. K.; Chatterjee, S.; Wolf, W.
Journal of Fluorine Chemistry, 1991 , vol. 55, # 3 p. 283 - 289
反应条件
sodium hydroxide in tetrahydrofuran 3 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 3 p. 249 - 256
反应条件
pyridine hydrogenfluoride in 1,4-dioxane
参考文献
Xia, Xiaoyang; Wang, Jianying; Hager, Michael W.; Sisti, Nicholas; Liotta, Dennis C.
Tetrahedron Letters, 1997 , vol. 38, # 7 p. 1111 - 1114
反应条件
sodium tetrahydroborate in ethanol T=0°C; 2.5 h;
参考文献
Tetrahedron, , vol. 40, # 1 p. 125 - 135
反应条件
4-(N,N-dimethlyamino)pyridine in N,N-dimethyl-formamide T=50°C; 4 h;
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 23, # 1-2 p. 7 - 29
反应条件
1: 24 percent / pyridine, H2O2 / CH2Cl2 / 1) -50 deg C, 5 min, 2) warm to 0 deg C, 0.5 h 2: 1) Na / 1a) THF, reflux, 4 h, 1b) HMPA, heating, 3 h, 2) heating, 8 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 6 p. 2161 - 2165
反应条件
1: pyridine 2: 17 percent / NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 19 p. 2695 - 2698
反应条件
1: Na 2: 70 percent / NaH / dimethylformamide 3: 63 percent / Rh(PPh3)3Cl, pyridine / aq. ethanol / 5 h / Heating 4: 60 percent / pyridine*HF / dioxane View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 7 p. 1111 - 1114
反应条件
1: POCl3, N,N-dimethylaniline / Heating 2: Na 3: 70 percent / NaH / dimethylformamide 4: 63 percent / Rh(PPh3)3Cl, pyridine / aq. ethanol / 5 h / Heating 5: 60 percent / pyridine*HF / dioxane View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 7 p. 1111 - 1114
