1-(二甲氧基甲基)吡咯烷合成路线 （共 10 条）
反应条件
in 1,2-dichloro-ethane T=30°C; 25 h;
参考文献
Vorbrueggen, Helmut
Synlett, 2008 , # 11 p. 1603 - 1617
反应条件
nitrogen in methanol; N,N-dimethyl-formamide
参考文献
Hoffmann-La Roche Inc.
Patent: US3976639 A1, 1976 ;
反应条件
1: 70 percent 2: 30 percent / 50 percent aq. NaOH, triethylamine / CHCl3 / 4 h / 30 - 35 °C View Scheme
参考文献
Schroth, W.; Kluge, H.; Frach, R.; Hodek, W.; Schaedler, H. D.
Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 5 p. 787 - 802
参考文献
Ionkin, A. S.; Arbuzov, B. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 7.2 p. 1489 - 1491
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 7 p. 1639 - 1641
反应条件
1: T=50 - 80°C; 3 h; Inert atmosphere;
2: With sodium methylate in methanol
T=-5 - 5°C; 4.5 h; Inert atmosphere;
参考文献
Yao, Bangben; Zhang, Yuhong; Li, Yong
Journal of Organic Chemistry, 2010 , vol. 75, # 13 p. 4554 - 4561
反应条件
2.) methanol, RT, overnight; Yield given. Multistep reaction;
参考文献
Theisen; McCollum; Andrus
Nucleosides and Nucleotides, 1993 , vol. 12, # 10 p. 1033 - 1046
参考文献
Schroth, W.; Kluge, H.; Frach, R.; Hodek, W.; Schaedler, H. D.
Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 5 p. 787 - 802
反应条件
in methanol
0.166667 h; Heating;
参考文献
Knoll, Alexander; Liebscher, Juergen
Synthesis, 1984 , # 1 p. 51 - 53
参考文献
Kantlehner, Willi; Haug, Erwin; Speh, Peter; Braeuner, Hans-Juergen
Synthesis, 1985 , # 1 p. 60 - 62
反应条件
in diethyl ether
6 h; Ambient temperature;
参考文献
Ahuja; Singh; Asthana; Sardana; Anand
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 12 p. 1034 - 1038
